From
http://www.diabloii.net/pressdesk/bl...t-03-06-19.php


About rune



Q: Will higher level runes be easier to get?

Blizzard: Yes, thanks to the new Horadric Cube recipes. Also, the Hellforge quest now drops better runes, the Countess drops better runes, and the rune drops themselves have been improved to be more likely to drop better runes.


Q: Will there be Horadric cube recipes that let you upgrade all the way to a Zod rune?

Blizzard: Yes.