(Yes it's Predator from the video game because these are duels between video game characters.)

Initially, I would root for Samus and bet on Predator, but after considering her arsenal, I'm going to have to say definately Samus.

She does have more experience in the gaming industry than Predator. Correct me if I'm missing something, but she has 4 games as well as being a character in both Smash Brothers games.

As Raziel stated, she does have many, many weapons. Also, as stated in one of the Zelaron Battle introduction threads, Samus has all of her weapons from all games besides the special ones obtained at the end of a game.

Samus would simply overwhelm Predator with weaponry.

What is it they say about silence being golden?