Weapons & Armor
Iron Sword- A typical blade, not extremely powerful.
The Axes- Allows Kain to use a deadly melee attack.
Mace- A Mace that is somewhat powerful and that can be used to destroy barriers and so-on.
Soul Reaver- The most powerful weapon Kain wields. Capable of destroying an enemy in one powerful stroke.
Blood Reaver- Not as powerful. Kain can destroy objects with this blade and it can be used in deadly combinations, but it lacks in strength compared to the Soul Reaver.
Flame Sword- A blade of fire that incinerates Kain's opponents. In Blood Omen, it was even more useful because it can strike opponents faster and Kain can use magic.
Bone Armor- No good.
Iron Armor- Armor forged by hellfire and the Necromancer Mortanius' magics. It is not all that useful.
Flesh Armor- Allows Kain to concentrate on his opponent, killing them while the armor draws out the blood for him.
Chaos Armor- Kains' enemies are quite vicious and the Chaoss Armor extracts a heavy price for their bloodlust. They may be striking him, but it is their body that carries the wounds.
Wraith Armor- Found in "Hell" this armor was forged by the Spirit Forges and gives Kain great defense when it is night. At day, it is useless.

Kain's power is at its peak when it is night. When daylight chases darkness, the vampire's power wanes. Still, Kain is no weakling. Of course, I have already stated that the blade Kain wields and his own physical strength won't help much here. His powerful TK and Magic is his only chance.

Samus could launch herself into the air and hit him constantly with those beams of hers and so-on. Kain could probably avoid most of them with Jump. However, Slow Time seems more useful. Slow time and those missiles are stuck. Then, move out of the way and behind Samus. Also, what if his TK could be used to set off the time-frozen missiles? He could detonate them right in Samus' face. Or, he could move the missiles right back at her.

If that's no good, he could simply grab her body with TK, time is still slowed, and fling her to the ground. Then, the Soul Reaver/Reaver could end this once and for all.