If you want to do a lot of magic, it's Bretton or high elf for you, otherwise you'll never have the mana pool to do much of anything. You do not want acrobatics or athletics as major skills, as you'll level up faster than you can earn strength multiplier. Also, choose weapon skill or destruction, not both. If you use both a lot, you won't level up either very quickly. If you don't use it alot, you don't need it as a major skill. Take restoration; you'll be glad you did. Take an armor skill; you don't honestly think you won't get hit, do you?

If you still plan on doing axes and destruction, still don't choose destruction as a major skill. You can easily level up destruction with a Fire Damage 1pt on Self spell (you only gain skill exp if the effect was sucessful) without worrying about leveling up without a good strength multiplier, and you can just make a point of buying weapon skill training each level to keep the strength up.