Jamie Lynn Spears (britney's sister) is Preg-O

The bone thing dosent effect everyone... And when it does they're not usually very bad cases. But your not supposed to be on it for i think, more than 5 years?

While it has long been known that Depo-Provera causes bone loss, it has recently been discovered that the osteoporotic effects of the injection grow worse the longer Depo-Provera is administered, may remain long after the injections are stopped, and may be irreversible. For this reason, on November 17, 2004 the United States Food and Drug Administration and Pfizer agreed to put a "black box warning" on Depo-Provera's label.[28] However, the World Health Organization (WHO) advises that the use of Depo-Provera should not be restricted.[29][30]

My girlfriend has been on Depo-provera for a while, and actually has missed her last shot, a few months late so we've had to be more careful recently.. And I do feel it has screwed with her sex drive and emotional status, it seemed to have set a time bomb off in her head.